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Orbenin L.A.

Orbenin L.A. is a lactating cow intramammary antibiotic infusion with prolonged action. Orbenin L.A. is bactericidal and is indicated for use against important bacteria commonly associated with bovine Mastitis, including penicillin resistant organisms. The duration of treatment makes Orbenin L.A. particularly useful when Staphylococci are known or suspected to be involved.

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  • Approved uses/Indications

    Orbenin L.A. is for the treatment of bovine mastitis (caused by Gram+ve bacteria) in the lactating cow. Particularly indicated for the treatment of staphylococcal infections, when the sustained bactericidal action against both penicillin-resistant and sensitive strains will meet with the strict requirements for successful therapy.

    Orbenin L.A. is active against Gram+ve organisms associated with mastitis. It is highly effective against Streptococcus agalactiae and other streptococcal species, penicillin-resistant and sensitive Staphylococci and Corynebacterium pyogenes. Unlike natural penicillins, cloxacillin is not destroyed by ß-lactamase. It is therefore active against penicillin-resistant Staphylococci, which are an important cause of mastitis.

  • Packaging

    Orbenin L.A. is a stable suspension containing 200mg cloxacillin (a semi-synthetic penicillin), as the sodium salt, in a long-acting base.

    Orbenin L.A. is presented as cartons of 24 x 3g syringes suitable for intramammary infusion.

  • Dosage & Administration

    Orbenin L.A. comes with a nozzle adaptor to give you the choice of short or conventional nozzle length. Use of a short nozzle avoids full penetration of the teat canal; where practical this option is recommended.

    • Apply one syringe every 48 hours for 3 treatments per infected quarter. An alternative regime is to apply one syringe every 24 hours for 5 treatments per infected quarter. For further guidance, please contact your veterinarian.
    • After milking, clean and disinfect the teat, paying particular attention to the teat end.
    • Remove the cap and ensure the sterile exposed nozzle does not touch anything.
    • Insert the nozzle carefully into the teat canal and gently express the antibiotic into the quarter.
    • Dip or spray each teat with a licensed teat dip or spray.
    • The treated quarter(s) may be milked out at the next normal milking and the milk discarded.
  • Precautions

    Drying off: Orbenin LA may be used at drying off where the dry period is expected to be less than 30 days. For longer dry periods use ORBENIN* DRY COW (ACVM No A0888) or ORBENIN* ENDURO (ACVM No A6036).

    For 3 x 48 hourly treatments

    MILK: Milk intended for sale for human consumption must be discarded during treatment for not less than 7 milkings or approximately 84 hours following the last treatment when cows are milked twice daily.

    MILK: Milk intended for sale for human consumption must be discarded during treatment for not less than 3 milkings or approximately 72 hours following the last treatment when cows are milked once daily.

    MEAT: Cattle producing meat or offal for human consumption must not be sold for slaughter either during treatment or within 3 days of cessation of the last treatment.

    For 5 x 24 hourly treatments

    MILK: Milk intended for sale for human consumption must be discarded during treatment for not less than 8 milkings or approximately 96 hours following the last treatment when cows are milked twice daily.

    MILK: Milk intended for sale for human consumption must be discarded during treatment for not less than 4 milkings or approximately 96 hours following the last treatment when cows are milked once daily.

    MEAT: Cattle producing meat or offal for human consumption must not be sold for slaughter either during treatment or within 3 days of cessation of the last treatment.

    Bobby Calves: Milk taken from cows during treatment within the withholding period must not be fed to bobby calves.

    Penicillins may cause hypersensitivity (allergy) following inhalation, ingestion or skin contact. Do not handle this product if you know you are sensitised to, or if you have been advised not to work with, such preparations. Handle this product with great care to avoid exposure, taking all recommended precautions, including the use of suitable protective clothing and gloves.

  • Mandatories

    Zoetis Animal Health New Zealand Limited. Level 5, 8 Mahuhu Crescent, Auckland 1010, New Zealand. Tel: 0800 650 277, Fax: 0800 628 629. ORBENIN is a registered trade mark of GlaxoSmithKline NZ Ltd. ACVM Registration No. A3664. RVM; Available only under Veterinary Authorisation.

    References:

    1. Zoetis Animal Health Trial (Buswell 1974).
    2. Wilson et al (1972) British Veterinary Journal 128, 71-85.
    3. Brander et al (1964) Veterinary Record 76, 329-330.
  • Contact Information

    For technical enquiries please phone Zoetis Technical Services on 0800 650 277.