Do not administer to pregnant animals unless abortion is intended. Induced parturition may precipitate dystocia, foetal death, retained placenta or metritis. Induction of parturition in swine earlier than 72 hours prior to the predicted farrowing date may result in piglet mortality. Do not administer intravenously.
25mg/day for 10 days in cattle gave no effect on haematology or clinical chemistry. There was an increase in heart rate and rectal temperature but no gross lesions at necropsy. At luteolytic doses it did not impair fertility of cattle and had no effect on progeny. In adult mares, 400–800mg/day for 8 days gave reduced sensitivity to pain; locomotor in-coordination; hypergastromotility; sweating; hyperthermia; laboured respiration; elevated cholesterol, glucose, bilirubin, haemoglobin and erythrocytes, but reduced eosinophils. No adverse effects were sustained.
Cattle: Sometimes salivation and increased rectal temperature may occur.
Horses: May sweat and have decreased rectal temperature, increased heart and respiratory rates, abdominal pain and in-coordination. These symptoms appear within 15 minutes and disappear within 1 hour.
Pigs: Increased body temperature and respiration, salivation, restlessness, defecation and urination in pregnant sows.
Not for human use. Keep away from pregnant women, asthmatics or persons with respiratory problems. If spilt on skin, wash off immediately with soap and water.